Ethylene vinyl cawv (EVOH) (Lava) yog copolymer nrog dimethyl sulfoxide (DMSO) hnyav thiab raug tshem tawm ntawm (radiopaque) micronized tantalum hmoov. Thaum txhaj los ntawm ib lub catheter thiab tov nrog cov ntshav, cov kuab tshuaj yog diluted, precipitating lub copolymer rau hauv ib tug spongy cam khwb cia nrog ib tug zoo li gel zoo li. Qhov no ua rau vascular occlusion ntawm tus nqi qeeb dua li cov kua nplaum.
Lava yog tsim nyob rau hauv ntau yam viscosities (Lava-12/18/34), uas tuaj yeem xaiv rau lub hom phiaj xav tau. Piv txwv li, Lava-34 nrog qis viscosity yog cov kua dej ntau dua rau cov microvessles distal, Lava-18 nrog cov qauv qauv rau kev siv dav dav, thaum Lava-34 nrog cov viscosity siab dua rau cov hlab ntsha siab. Lava yuav tsum tau agitated los xyuas kom meej qhov sib tov yog uniform thiab ces yuav tsum tau txhaj ntawm ib tug catheter rau hauv lub vascular tsob ntoo yuav tsum tau. Cov koob txhaj tshuaj tshwj xeeb thiab cov catheter yog siv vim tias DMSO cov kuab tshuaj tuaj yeem ua rau cov khoom siv tsis zoo. Muaj tsawg dua ntawm cov lus teb inflammatory nrog Lava thaum piv nrog cov kua nplaum. Raws li Lava yog nonadhesive, qhov kev pheej hmoo ntawm kev thaiv thiab kev nkag ntawm lub catheter yog qhov kev txhawj xeeb tsawg dua piv rau kev siv cov kua nplaum. Lava tuaj yeem txhaj tshuaj tsis tu ncua siv tib lub catheter los ntsuas qhov kev nce qib fluoroscopically. Ib qho me me ntawm cov ntaub ntawv polymer gel nyob ib ncig ntawm lub taub hau catheter, uas tsim cov tawv nqaij ntawm qhov sib txuam ntawm cov sib tov thiab cov ntshav. Raws li ntau embolic yog txhaj, qhov no nthuav, tsim nruam rupture thiab reskinning ntawm lub embolus, uas ua rau ib tug lava zoo li ntws ntawm embolic, them ib tug ntau dua kev tswj ntawm cov kua nplaum. Lava tau siv rau embolization ntawm AVMs thiab hypervascular hlav.
