LavaTMNeurovascular Liquid Embolic Agent yog Iis tsim los ntawm ethylene vinyl cawv copolymer (EVOH) yaj hauv dimethyl sulphoxide (DMSO) thiab nrog (tshem tawm) micronised tantalum hmoov rau radiopacity. Cov khoom no yog npaj los muab lwm txoj hauv kev rau cov pa nplaum embolic cov neeg ua haujlwm uas siv rau peripheral embolization. Kev siv cov tshuaj nplaum embolic hauv cov txheej txheem peripheral embolization tau cuam tshuam nrog ntau yam teeb meem, suav nrog kev tshem tawm cov kab mob embolic los ntawm qhov chaw txhaj tshuaj thiab lawv tsiv mus rau lwm thaj chaw ntawm lub cev. Tus neeg sawv cev uas tsis yog-adhesive embolization no kov yeej cov teeb meem no los ntawm kev muab txoj hauv kev nyab xeeb thiab zoo dua ntawm peripheral embolization.
Ethylene vinyl cawv copolymer yog biocompatible polymer uas tau siv dav hauv ntau daim ntawv thov kev kho mob. Nws muaj kev ruaj ntseg siab thiab tiv taus kev degradation, uas ua rau nws yog qhov kev xaiv zoo tshaj plaws rau kev siv cov tshuaj embolic. Thaum siv ua ke nrog dimethyl sulphoxide, nws tsim ib qho tsis-nplaum, kua embolic tus neeg sawv cev uas tuaj yeem raug xa mus rau qhov chaw ntawm embolization.Qhov sib ntxiv ntawm micronized tantalum hmoov rau cov khoom no muab cov khoom siv radiopaque uas tso cai rau cov kws kho mob pom qhov chaw ntawm tus neeg sawv cev embolic thaum lub sijhawm ua haujlwm. Qhov no ua kom ntseeg tau tias tus neeg sawv cev embolic tau raug muab tso rau, thiab tsis muaj kev pheej hmoo ntawm kev tsiv teb tsaws mus rau lwm thaj chaw ntawm lub cev. Qhov no tsis yog-adhesive kua embolic tus neeg saib xyuas muaj ntau yam kev pab cuam tshaj li cov pa adhesive agents. Ua ntej, nws cov xwm txheej tsis-nplaum txo qhov kev pheej hmoo ntawm cov teeb meem cuam tshuam nrog kev tshem tawm thiab tsiv teb tsaws ntawm cov neeg ua haujlwm embolic. Qhov thib ob, nws muab txoj hauv kev meej dua ntawm embolization vim nws cov kua dej, uas tso cai rau kev tswj hwm zoo dua thaum txhaj tshuaj. Thaum kawg, kev siv cov tshuaj radiopaque tantalum hmoov ua kom ntseeg tau tias tus neeg sawv cev embolic yog qhov raug thiab tsis muaj kev pheej hmoo ntawm kev tsiv teb tsaws.
Khoom nta
1. Cov khoom tsis yog nplaum
- Cov tshuaj uas tsis yog-adhesive ua kua embolic muaj cov tshuaj tiv thaiv tsawg, ua rau lawv yooj yim dua los txhaj thiab tsis tshua muaj teeb meem xws li hlab ntsha tawg. Tsis tas li ntawd, lawv qhov xwm txheej tsis yog nplaum tso cai rau kev tshem tawm cov catheter kom zoo dua thiab muaj kev nyab xeeb dua tom qab cov txheej txheem.
2. Cim Tsawg-Viscosity Formulation nrog ntau tus qauv
- Cov tshuaj uas tsis yog-adhesive ua kua embolic muaj nyob rau hauv ntau cov qauv nrog cov qauv uas tsis muaj viscosity xws li LAVA-12, LAVA-18, thiab LAVA-34. Cov formulations tso cai rau kev tswj kom zoo dua thaum txhaj tshuaj, nce precision, thiab kev pom zoo ntawm cov hlab ntsha pathological. Yog li ntawd, ntau yam ntawm cov qauv thiab cov qauv ua kom ntseeg tau tias cov kws kho mob tuaj yeem kho lawv txoj hauv kev rau txhua tus neeg mob, yog li ua kom cov txheej txheem ua tiav.
3. Zoo dua Dispersibility thiab nkag mus
- Lava tau txhim kho dispersibility thiab nkag mus rau lub zog. Lawv tuaj yeem nkag mus tob rau hauv cov hlab ntsha pathological, nkag mus txawm tias cov microvessels ntawm qhov kawg ntawm qhov txhab. Kev txhim kho dispersibility thiab nkag mus rau lub zog kuj txhais tau hais tias tus neeg sawv cev ua rau muaj qhov tsis sib xws thiab cov crevices nyob rau hauv cov hlab ntsha txawv txav, ua rau muaj kev ua tiav ntau dua.
2. Pom tau zoo heev
- Cov tshuaj uas tsis yog-adhesive ua kua embolic muaj nyob rau hauv ntau cov qauv nrog cov qauv uas tsis muaj viscosity xws li LAVA-12, LAVA-18, thiab LAVA-34. Cov formulations tso cai rau kev tswj kom zoo dua thaum txhaj tshuaj, nce precision, thiab kev pom zoo ntawm cov hlab ntsha pathological. Yog li ntawd, ntau yam ntawm cov qauv thiab cov qauv ua kom ntseeg tau tias cov kws kho mob tuaj yeem kho lawv txoj hauv kev rau txhua tus neeg mob, yog li ua kom cov txheej txheem ua tiav.
Khoom Parameter
